Current progress of oral site-specific dosage forms: Emphasis on gastroretentive drug delivery systems

Gastroretentive drug delivery systems: a review

The purpose of writing this review on gastroretentive drug delivery systems was to compile the recent literature with special focus on various gastroretentive approaches that have recently become leading methodologies in the field of site-specific orally administered controlled release drug delivery. In order to understand various physiological difficulties to achieve gastric retention, we have...

Gastroretentive Drug Delivery Systems: a Promising Approach

An overview on various approaches to Gastroretentive dosage forms

Over the past four decades, gastro retentive dosage forms have recently become a leading methodology in the field of site-specific orally administered controlled release drug delivery system.. Gastroretentive dosage forms have the potential to improve local therapy with an increase of short gastric residence time and unpredictable gastric emptying time and decrease the variation in bioavailabil...

An Overview on Polymethacrylate Polymers in Gastroretentive Dosage Forms

Drugs with lower bioavailability need repeated dosing to reach the minimum effective therapeutic concentration in plasma. In order to retain the drug in upper part of gastro intestinal tract (GIT) which is the major absorption window for majority of drugs and also to have localized effect many advances in drug delivery were made. Researchers mainly emphasize on to get patient compliance by form...

An Overview on Gastroretentive Drug Delivery System

Oral controlled release and site specific drug delivery system has been of great interest in pharmaceutical field to achieve improved therapeutic advantage. Drug absorption in the gastrointestinal tract is a highly variable procedure and prolonging gastric retention of the dosage form extends the time for drug absorption. Gastro retentive drug delivery system is one of such novel approaches to ...